BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 760K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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14 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a Novel Selective and Cell-Active N6-Methyladenosine RNA Demethylase ALKBH5 Inhibitor.EBI
Sun Yat-sen University
Discovery of the salicylaldehyde-based compound DDO-02267 as a lysine-targeting covalent inhibitor of ALKBH5.EBI
China Pharmaceutical University
Discovery of maleimide derivatives as m6A demethylase ALKBH5 inhibitors.EBI
China Pharmaceutical University
Discovery and structure-activity relationship study of nicotinamide derivatives as DNA demethylase ALKBH2 inhibitors.EBI
Sichuan University
Small molecules that regulate the N6-methyladenosine RNA modification as potential anti-cancer agents.EBI
University of Connecticut
Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity.EBI
Sichuan University
Discovery of Pyrazolo[1,5-EBI
China Pharmaceutical University
Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.EBI
University College London
Rational Design and Optimization of mEBI
University of California San Diego
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach.EBI
Kyoto Prefectural University of Medicine
Discovery of a potent, selective and cell active inhibitor of mEBI
Nankai University
Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study.EBI
Nankai University
Novel Small Molecule RNA m6A Demethylase AlkBH5 Inhibitors for Treating Cancer.EBI
Smith, Gambrell & Russell
1-(5-(2-CYANOPYRIDIN-4-YL)OXAZOLE-2-CARBONYL)-4-METHYLHEXAHYDROPYRROLO[3,4-B]PYR ROLE-5(1H)-CARBONITRILE AS USP30 INHIBITOR FOR USE IN THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION, CANCER AND FIBROSISBDB
Mission Therapeutics