Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50023680
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666695BDBM50666695(CHEMBL6177799)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666699BDBM50666699(CHEMBL6174808)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataKd:  5.99E+3nMAssay Description:Binding affinity to recombinant hexahistidine-tagged wild type ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666701BDBM50666701(CHEMBL6167259)
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666698BDBM50666698(CHEMBL6177151)
Affinity DataIC50: 8.53E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666702BDBM50666702(CHEMBL6177073)
Affinity DataIC50: 8.66E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666694BDBM50666694(CHEMBL6177391)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666703BDBM50666703(CHEMBL6176010)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26121BDBM26121(Succinic acid, 6 | butanedioic acid | Succinate | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of ALKBH3 (unknown origin) using (5'-FAM-d(CAT)r(GGACm1A)d(TATGT)-3'BHQ1) as substrate preincubated with compound followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666697BDBM50666697(CHEMBL6168298)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666696BDBM50666696(CHEMBL6177107)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of FTO (31 to 505 residues) (unknown origin) using (5'FAM-d(CAT)r(GGm6ACA)d(TATGT)-3'BHQ1) as substrate preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666694BDBM50666694(CHEMBL6177391)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of FTO (31 to 505 residues) (unknown origin) using (5'FAM-d(CAT)r(GGm6ACA)d(TATGT)-3'BHQ1) as substrate preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26113BDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14672BDBM14672(cid_311 | CITRIC ACID | 2-hydroxypropane-1,2,3-tri...)
Affinity DataIC50: 4.88E+5nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed