Compile Data Set for Download or QSAR
Report error Found 6592 for UniProtKB: Q9HBB4
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666041BDBM50666041(CHEMBL6171901)
Affinity DataKi: <0.0500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662476BDBM50662476(CHEMBL6151959)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 515786BDBM515786(US11053225, Compound 69)
Affinity DataIC50: 0.120nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384584BDBM50384584(CHEMBL2036807 | US9744172, Compound UNC607A)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 497267BDBM497267((2,6-dimethylpyridin-4- yl)(4-(7-((1R,4S)-4- hydro...)
Affinity DataKi:  0.190nMAssay Description:ATP competitive inhibition of MERTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662464BDBM50662464(CHEMBL6163959)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662470BDBM50662470(CHEMBL6170266)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662473BDBM50662473(CHEMBL6146201)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384583BDBM50384583(CHEMBL2036806)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355504BDBM50355504(CHEMBL1908393)
Affinity DataKd:  0.270nMAssay Description:Binding constant for MERTK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221)
Affinity DataIC50: 0.290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662475BDBM50662475(CHEMBL6161683)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298823BDBM298823(US10125118, Example 229 | US10947215, Example 229)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662461BDBM50662461(CHEMBL6172586)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662471BDBM50662471(CHEMBL6173640)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055499BDBM50055499(CHEMBL3326002)
Affinity DataKi:  0.330nMAssay Description:Inhibition of Mer (unknown origin) by Off-chip Mobility Shift AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 515821BDBM515821(US11053225, Compound 102)
Affinity DataIC50: 0.360nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662462BDBM50662462(CHEMBL6171026)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662463BDBM50662463(CHEMBL6176439)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635615BDBM50635615(CHEMBL5542282)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MER (unknown origin) expressed in mouse BaF3 cells co-expressing TMEM assessed as inhibition of MER-driven cell proliferation incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350865BDBM350865(US9795606, B26 | UNC1667A | US10004755, Compound U...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308226BDBM308226(US9649309, Compound UNC4103A)
Affinity DataIC50: 0.430nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469353BDBM50469353(CHEMBL4283353)
Affinity DataKi:  0.430nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055496BDBM50055496(CHEMBL3326006)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308193BDBM308193(US9649309, Compound UNC2571A)
Affinity DataIC50: 0.470nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308186BDBM308186(US9649309, Compound UNC2550A)
Affinity DataIC50: 0.490nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625502BDBM50625502(Glesatinib | Mgcd-265 | MG-90265 | MG-90265X | MG9...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662875BDBM50662875(CHEMBL6166548)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172078BDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 628988BDBM628988(N-{3-fluoro-4-[(2-{[2-(4-methanesulfonylpiperazin-...)
Affinity DataIC50: 0.5nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662457BDBM50662457(CHEMBL6166016)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataEC50: <0.510nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662878BDBM50662878(CHEMBL6176437)
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350848BDBM350848(US9795606, B7 | UNC2078A | US10004755, Compound UN...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308189BDBM308189(US9649309, Compound UNC2547A)
Affinity DataIC50: 0.560nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384584BDBM50384584(CHEMBL2036807 | US9744172, Compound UNC607A)
Affinity DataKi:  0.560nMAssay Description:Inhibition of Mer using EFPIYDFLPAKKK-CONH2 as substrate by Michaelis-Menten equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055498BDBM50055498(CHEMBL3326004 | US9795606, B28 | US10004755, Compo...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055498BDBM50055498(CHEMBL3326004 | US9795606, B28 | US10004755, Compo...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of Mer (unknown origin) by Off-chip Mobility Shift AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662466BDBM50662466(CHEMBL6165211)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469353BDBM50469353(CHEMBL4283353)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged MERTK (528 to 999 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 628989BDBM628989(N-{3-fluoro-4-[(2-{[2-(pyrrolidin-1-yl)pyrimidin-4...)
Affinity DataIC50: 0.600nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469353BDBM50469353(CHEMBL4283353)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298813BDBM298813(US10125118, Example 219 | US10947215, Example 219)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308318BDBM308318(US9649309, Compound UNC3667A)
Affinity DataIC50: 0.610nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308188BDBM308188(US9649309, Compound UNC2489A)
Affinity DataIC50: 0.630nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308349BDBM308349(US9649309, Compound UNC4160A)
Affinity DataIC50: 0.670nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444072BDBM50444072(CHEMBL3092793)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 308181BDBM308181(US9649309, Compound UNC2432A)
Affinity DataIC50: 0.690nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

Displayed 1 to 50 (of 6592 total ) | Next | Last >>
Jump to: