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Report error Found 50 of affinity data for UniProtKB/TrEMBL: Q5XLE3
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658100BDBM50658100(CHEMBL6152538)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658098BDBM50658098(CHEMBL6152503)
Affinity DataIC50: 53nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658099BDBM50658099(CHEMBL6145099)
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658106BDBM50658106(CHEMBL6145758)
Affinity DataIC50: 83nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658107BDBM50658107(CHEMBL6161609)
Affinity DataIC50: 89nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658095BDBM50658095(CHEMBL6143281)
Affinity DataIC50: 117nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataKd:  226nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658101BDBM50658101(CHEMBL6162317)
Affinity DataIC50: 245nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370785BDBM50370785(CHEMBL220743)
Affinity DataIC50: 248nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658096BDBM50658096(CHEMBL6160046)
Affinity DataIC50: 276nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658104BDBM50658104(CHEMBL6147124)
Affinity DataIC50: 378nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658105BDBM50658105(CHEMBL6147620)
Affinity DataIC50: 527nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658088BDBM50658088(CHEMBL6147098)
Affinity DataIC50: 851nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658091BDBM50658091(CHEMBL6145411)
Affinity DataIC50: 949nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658094BDBM50658094(CHEMBL6163247)
Affinity DataIC50: 1.23E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 1.48E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658092BDBM50658092(CHEMBL6141625)
Affinity DataIC50: 1.51E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658090BDBM50658090(CHEMBL6166325)
Affinity DataIC50: 3.32E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32021BDBM32021(RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human ALKBH2 by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32021BDBM32021(RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...)
Affinity DataIC50: 9.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416766BDBM50416766(CHEMBL5285500)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.38E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416765BDBM50416765(CHEMBL5269140)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596053BDBM50596053(CHEMBL5173876)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658087BDBM50658087(CHEMBL6168150)
Affinity DataIC50: 3.44E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658086BDBM50658086(CHEMBL6144735)
Affinity DataIC50: 3.65E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416762BDBM50416762(CHEMBL5288180)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416836BDBM50416836(CHEMBL5288308)
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416763BDBM50416763(CHEMBL5282569)
Affinity DataIC50: 5.64E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416764BDBM50416764(CHEMBL5266761)
Affinity DataIC50: 5.66E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658093BDBM50658093(CHEMBL6145999)
Affinity DataIC50: 6.03E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416761BDBM50416761(CHEMBL5286685)
Affinity DataIC50: 6.52E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658102BDBM50658102(CHEMBL6150956)
Affinity DataIC50: 7.48E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658089BDBM50658089(CHEMBL6151900)
Affinity DataIC50: 7.53E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416767BDBM50416767(CHEMBL5276266)
Affinity DataIC50: 8.53E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21615BDBM21615(1-phenyl-1H-pyrazole-4-carboxylic acid | Pyrazole,...)
Affinity DataIC50: 8.67E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658103BDBM50658103(CHEMBL6150210)
Affinity DataIC50: 9.74E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22971BDBM22971(Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ALKBH2 demethylase activity by restriction endonuclease digestion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416768BDBM50416768(CHEMBL5283651)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26106BDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344962BDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | L-2-Hydroxygluta...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of N-terminal His-tagged human full length ALKBH2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416550BDBM50416550(CHEMBL5274121)
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361471BDBM50361471(CHEMBL1614745)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of ABH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646993BDBM50646993(CHEMBL5594860)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of demethylation of 6xHis-tagged human ALKBH2 (56 to 261 residues) extracted from Escherichia coli BL21(DE3) by electrophoretic analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361471BDBM50361471(CHEMBL1614745)
Affinity DataIC50: 4.24E+5nMAssay Description:Inhibition of ABH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361471BDBM50361471(CHEMBL1614745)
Affinity DataIC50: 4.24E+5nMAssay Description:Inhibition of N-terminal His-tagged human full length ALKBH2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed