Compile Data Set for Download or QSAR
Report error Found 93 of affinity data for UniProtKB/TrEMBL: P49959
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659218BDBM50659218(CHEMBL6163352)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659210BDBM50659210(CHEMBL6165723)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659217BDBM50659217(CHEMBL6168876)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659228BDBM50659228(CHEMBL6162618)
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659220BDBM50659220(CHEMBL6151731)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659222BDBM50659222(CHEMBL6147664)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659211BDBM50659211(CHEMBL6143243)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659212BDBM50659212(CHEMBL6162300)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659223BDBM50659223(CHEMBL6163199)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659227BDBM50659227(CHEMBL6170447)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659225BDBM50659225(CHEMBL6163101)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659213BDBM50659213(CHEMBL6149785)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573124BDBM573124(US11453663, Preparative Example 167 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573125BDBM573125(US11453663, Preparative Example 168 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573130BDBM573130(US11453663, Preparative Example 173 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573131BDBM573131(US11453663, Preparative Example 174 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573128BDBM573128(US11453663, Preparative Example 171 | 2-cyano-N-(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572574BDBM572574(US11453663, Preparative Example 135 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573129BDBM573129(US11453663, Preparative Example 172 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572983BDBM572983(US11453663, Preparative Example 160 | 2-cyano-N-(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573122BDBM573122(US11453663, Preparative Example 165 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572770BDBM572770(US11453663, Preparative Example 148 | 3-(2-bromo-3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659224BDBM50659224(CHEMBL6148530)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659229BDBM50659229(CHEMBL6143926)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659219BDBM50659219(CHEMBL6150580)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  2.59E+3nMAssay Description:Binding affinity to human MRE11A incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659216BDBM50659216(CHEMBL6170312)
Affinity DataIC50: 2.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572839BDBM572839(US11453663, Preparative Example 157 | 2-cyano-3-(3...)
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572707BDBM572707(US11453663, Preparative Example 141 | 2-(3,4-dihyd...)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659215BDBM50659215(CHEMBL6170744)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572528BDBM572528(US11453663, Preparative Example 130 | 2-cyano-3-(3...)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633491BDBM50633491(CHEMBL5400171)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to his-tagged recombinant human MRE11 assessed as dissociation constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573127BDBM573127(US11453663, Preparative Example 170 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573132BDBM573132(US11453663, Preparative Example 175 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572799BDBM572799(US11453663, Preparative Example 152 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572800BDBM572800(US11453663, Preparative Example 153 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572838BDBM572838(US11453663, Preparative Example 156 | 3-(3-chloro-...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572839BDBM572839(US11453663, Preparative Example 157 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572801BDBM572801(US11453663, Preparative Example 154 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573119BDBM573119(US11453663, Preparative Example 161 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572844BDBM572844(US11453663, Preparative Example 158 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572848BDBM572848(US11453663, Preparative Example 159 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573123BDBM573123(US11453663, Preparative Example 166 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573120BDBM573120(US11453663, Preparative Example 162 | N-(4-(3-chlo...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 573121BDBM573121(US11453663, Preparative Example 164 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572545BDBM572545(US11453663, Preparative Example 133 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572573BDBM572573(US11453663, Preparative Example 134 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572537BDBM572537(US11453663, Preparative Example 131 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

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