Compile Data Set for Download or QSAR
Report error Found 39 of affinity data for UniProtKB/TrEMBL: E9Q6R7
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401641BDBM50401641(CHEMBL6083105)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378931BDBM50378931(CHEMBL6101820)
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378929BDBM50378929(CHEMBL6083109)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401638BDBM50401638(CHEMBL6103438)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393082BDBM50393082(CHEMBL6133073)
Affinity DataIC50: 4.44E+3nMAssay Description:Antagonist activity at human ERbeta LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401640BDBM50401640(CHEMBL6091991)
Affinity DataIC50: 4.71E+3nMAssay Description:Agonist activity at human PPARdelta LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393093BDBM50393093(CHEMBL6074549)
Affinity DataIC50: 4.94E+3nMAssay Description:Antagonist activity at human ERRalpha LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535379BDBM50535379(CHEMBL4445722)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535379BDBM50535379(CHEMBL4445722)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378930BDBM50378930(CHEMBL6083108)
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21724BDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21724BDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535382BDBM50535382(CHEMBL4588863)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535382BDBM50535382(CHEMBL4588863)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393092BDBM50393092(CHEMBL6078316)
Affinity DataIC50: 6.63E+3nMAssay Description:Antagonist activity at human ERRgamma LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataIC50: 6.65E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393092BDBM50393092(CHEMBL6078316)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393081BDBM50393081(CHEMBL6103234)
Affinity DataIC50: 6.83E+3nMAssay Description:Inhibition of Jak3-mediated IL15-induced Stat5 phosphorylation in human MO7 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393030BDBM50393030(CHEMBL6102492)
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataIC50: 7.04E+3nMAssay Description:Antagonist activity at human RXRalpha LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393027BDBM50393027(CHEMBL6120230)
Affinity DataIC50: 7.63E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378936BDBM50378936(CHEMBL6101988)
Affinity DataIC50: 7.63E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535379BDBM50535379(CHEMBL4445722)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393028BDBM50393028(CHEMBL6134519)
Affinity DataIC50: 8.85E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378928BDBM50378928(CHEMBL6120333)
Affinity DataIC50: 9.23E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378932BDBM50378932(CHEMBL6114912)
Affinity DataIC50: 9.68E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393032BDBM50393032(CHEMBL6091798)
Affinity DataIC50: 1.02E+4nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401637BDBM50401637(CHEMBL6102829)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401639BDBM50401639(CHEMBL6102803)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393094BDBM50393094(CHEMBL6074482)
Affinity DataIC50: 1.77E+4nMAssay Description:Agonist activity at human PPARalpha LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535381BDBM50535381(CHEMBL4591419)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535381BDBM50535381(CHEMBL4591419)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378935BDBM50378935(CHEMBL6078507)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378934BDBM50378934(CHEMBL6102548)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401636BDBM50401636(CHEMBL6108957)
Affinity DataIC50: 4.61E+4nMAssay Description:Agonist activity at human PPARgamma LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393081BDBM50393081(CHEMBL6103234)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378933BDBM50378933(CHEMBL6102218)
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed