Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50023824
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HSD17B13 (unknown origin)More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of mouse HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 68nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 74nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 77nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of mouse HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 89nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of N/C terminal 10 his tagged human HSD17B13 (2 to 300 residues) expressed in Expi293 using beta-estradiol and FAC-NAD+ as substrate incub...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of mouse HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 188nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 201nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 213nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 222nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 224nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair



































3D Structure (crystal)



