Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50023765
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667976BDBM50667976(CHEMBL6193303)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667980BDBM50667980(CHEMBL6192394)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667977BDBM50667977(CHEMBL6190576)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667978BDBM50667978(CHEMBL6189893)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667979BDBM50667979(CHEMBL6192876)
Affinity DataIC50: 2nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667975BDBM50667975(CHEMBL6192214)
Affinity DataIC50: 2nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed