Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50023354
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662321BDBM50662321(CHEMBL6149901)
Affinity DataIC50: 27nMAssay Description:Inhibition of AKR1C3 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662321BDBM50662321(CHEMBL6149901)
Affinity DataIC50: 27nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662320BDBM50662320(CHEMBL6162146)
Affinity DataIC50: 41nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662319BDBM50662319(CHEMBL6149085)
Affinity DataIC50: 62nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662318BDBM50662318(CHEMBL6172354)
Affinity DataIC50: 87nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662304BDBM50662304(CHEMBL6160315)
Affinity DataIC50: 330nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662309BDBM50662309(CHEMBL6165938)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662312BDBM50662312(CHEMBL6146171)
Affinity DataIC50: 510nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662302BDBM50662302(CHEMBL6167621)
Affinity DataIC50: 540nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662311BDBM50662311(CHEMBL6168271)
Affinity DataIC50: 620nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662313BDBM50662313(CHEMBL6134578)
Affinity DataIC50: 930nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662303BDBM50662303(CHEMBL6171978)
Affinity DataIC50: 950nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662308BDBM50662308(CHEMBL6162561)
Affinity DataIC50: 980nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662314BDBM50662314(CHEMBL6163212)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662301BDBM50662301(CHEMBL6151238)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662305BDBM50662305(CHEMBL6145170)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662306BDBM50662306(CHEMBL6145589)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662317BDBM50662317(CHEMBL6147792)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662329BDBM50662329(CHEMBL6170751)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662310BDBM50662310(CHEMBL6169327)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662315BDBM50662315(CHEMBL6172079)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662321BDBM50662321(CHEMBL6149901)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of AKR1C4 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662316BDBM50662316(CHEMBL6150454)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662326BDBM50662326(CHEMBL6161655)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662323BDBM50662323(CHEMBL6150482)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662327BDBM50662327(CHEMBL6160064)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662328BDBM50662328(CHEMBL6165153)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662324BDBM50662324(CHEMBL6171298)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662325BDBM50662325(CHEMBL6172449)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662307BDBM50662307(CHEMBL6159557)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342210BDBM50342210(4-(5-Phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662322BDBM50662322(CHEMBL6144050)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1C3 in human COLO 205 cells by Cell based AKR activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of AKR1C3 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342210BDBM50342210(4-(5-Phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of AKR1C3 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662321BDBM50662321(CHEMBL6149901)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of AKR1C2 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662321BDBM50662321(CHEMBL6149901)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of AKR1C1 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Texas at Austin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662322BDBM50662322(CHEMBL6144050)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of AKR1C3 (unknown origin) in human HEK293T cells assessed as turnover of coumberone to coumberol by live cell coumberone reduction assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed