Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50023817
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12D mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668629BDBM50668629(CHEMBL6189856)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of KRAS G12S mutant in human A549 cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668629BDBM50668629(CHEMBL6189856)
Affinity DataKi:  2.60E+4nMAssay Description:Binding affinity to human recombinant GDP-bound KRAS G12S mutant (1 to 169 residues) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed