Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50023603
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158154BDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBDNF/NT-3 growth factors receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158154BDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158154BDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 5nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158154BDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 11nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158154BDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 12nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665703BDBM50665703(CHEMBL6175562)
Affinity DataKd:  31nMAssay Description:Binding affinity to TRKA (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  36nMAssay Description:Binding affinity to TRKA (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  52nMAssay Description:Binding affinity to TRKA (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665703BDBM50665703(CHEMBL6175562)
Affinity DataKd:  60nMAssay Description:Binding affinity to TRKB (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataIC50: 70nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  150nMAssay Description:Binding affinity to TRKB (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665705BDBM50665705(CHEMBL6171921)
Affinity DataIC50: 177nMAssay Description:Inhibition of JAK2 (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665702BDBM50665702(CHEMBL6170053)
Affinity DataKd:  180nMAssay Description:Binding affinity to TRKB (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665702BDBM50665702(CHEMBL6170053)
Affinity DataKd:  220nMAssay Description:Binding affinity to TRKA (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665702BDBM50665702(CHEMBL6170053)
Affinity DataKd:  230nMAssay Description:Binding affinity to TRKC (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665703BDBM50665703(CHEMBL6175562)
Affinity DataKd:  280nMAssay Description:Binding affinity to TRKC (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665703BDBM50665703(CHEMBL6175562)
Affinity DataIC50: 361nMAssay Description:Inhibition of JAK2 (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  470nMAssay Description:Binding affinity to TRKC (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665704BDBM50665704(CHEMBL6177229)
Affinity DataIC50: 530nMAssay Description:Inhibition of JAK2 (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 576nMAssay Description:Inhibition of TNK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  640nMAssay Description:Binding affinity to SRC (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665702BDBM50665702(CHEMBL6170053)
Affinity DataIC50: 663nMAssay Description:Inhibition of JAK2 (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataIC50: 750nMAssay Description:Inhibition of MK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataIC50: 870nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to JAK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665704BDBM50665704(CHEMBL6177229)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of SRC (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665703BDBM50665703(CHEMBL6175562)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of SRC (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665701BDBM50665701(CHEMBL6174948)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665702BDBM50665702(CHEMBL6170053)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of SRC (unknown origin) by Z-LYTE Kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665700BDBM50665700(CHEMBL6175165)
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to ABL1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed