Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50023168
TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant human CA7 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of recombinant human CA7 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of recombinant human CA12 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 6(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human CA6 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant human CA2 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 6(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  15nMAssay Description:Inhibition of recombinant human CA6 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 13(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant human CA13 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 13(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant human CA13 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  24nMAssay Description:Inhibition of recombinant human CA12 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant human CA9 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  29nMAssay Description:Inhibition of recombinant human CA9 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant human CA9 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant human CA2 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 14(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  41nMAssay Description:Inhibition of recombinant human CA14 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  42nMAssay Description:Inhibition of recombinant human CA12 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 14(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  44nMAssay Description:Inhibition of recombinant human CA14 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  47nMAssay Description:Inhibition of recombinant human CA5B extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  47nMAssay Description:Inhibition of recombinant human CA5B extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human CA5B extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant human CA5A extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  63nMAssay Description:Inhibition of recombinant human CA5A extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 6(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  65nMAssay Description:Inhibition of recombinant human CA6 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human CA4 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  90nMAssay Description:Inhibition of recombinant human CA1 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 13(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  92nMAssay Description:Inhibition of recombinant human CA13 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 14(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  158nMAssay Description:Inhibition of recombinant human CA14 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant human CA1 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  406nMAssay Description:Inhibition of recombinant human CA2 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  701nMAssay Description:Inhibition of recombinant human CA5A extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  978nMAssay Description:Inhibition of recombinant human CA7 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of recombinant human CA4 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi:  2.72E+3nMAssay Description:Inhibition of recombinant human CA1 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  7.68E+3nMAssay Description:Inhibition of recombinant human CA4 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660087BDBM50660087(Veralipride | Veraliprida | Agradil | Agreal)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051565BDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 extracted from Escherichia coli BL21 (DE3) cells incubated for 15 mins by phenol red dye based stopped flow CO2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed