Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50023438
TargetGTPase KRas(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503649BDBM50503649(CHEMBL4476113)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Hexa-histidine KRAS G12C mutant (unknown origin) extracted from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652783BDBM50652783(CHEMBL5649162)
Affinity DataKi:  57nMAssay Description:Binding affinity to AKT2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50405636BDBM50405636(CHEMBL5282715)
Affinity DataKi:  59nMAssay Description:Binding affinity to AKT1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459706BDBM50459706(CHEMBL4214264)
Affinity DataIC50: 120nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of 6xHis-tagged human PTP1B catalytic domain using pNPP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 223197BDBM223197(2-Bromo-N-[3'-(1,1-dioxido-4-oxo-1,2,5-thiadia...)
Affinity DataIC50: 5.40E+4nMAssay Description:Reversible inhibition of human recombinant PTP1B catalytic domain (1 to 321 residues) transformed in Escherichia coli BL21 (DE3) measured for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataKi:  2.79E+5nMAssay Description:Binding affinity to SHP2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed