Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50023682
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652855BDBM652855((P)-7,7-dimethyl-4-(5- methyl-1H-indazol-4-yl)- 2-...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653180BDBM653180(US20240059703, Example 13-108 | (1R,9R)-6-(3-hydro...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653305BDBM653305(US20240059703, Example 14-76 | US20240059703, Exam...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652984BDBM652984(US20240059703, Example 2-76 | US20240059703, Examp...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653165BDBM653165(US20240059703, Example 13-114 | (6R,8R)-2-(2-acryl...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653113BDBM653113(US20240059703, Example 13-41 | 4-(3-hydroxy-1- nap...)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653255BDBM653255(1-(6-(4-(3-hydroxy-1- naphthalenyl)-3,7,7- trimeth...)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653297BDBM653297(US20240059703, Example 14-68 | US20240059703, Exam...)
Affinity DataIC50: 62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 653167BDBM653167(2-(2-acryloyl-2,6- diazaspiro[3.4]octan-6-yl)- 7,7...)
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 548334BDBM548334(WO2022093856, Example 1-29)
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666713BDBM50666713(CHEMBL6176460)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666714BDBM50666714(CHEMBL6175883)
Affinity DataIC50: 610nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652848BDBM652848(US20240059703, Example 1-1)
Affinity DataIC50: 690nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 548365BDBM548365(WO2022093856, Example 1-1 | WO2022093856, Example ...)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666716BDBM50666716(CHEMBL6176399)
Affinity DataIC50: 840nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652870BDBM652870(US20240059703, Example 1-23 | 1-(6-(4-(2-amino-1,3...)
Affinity DataIC50: 890nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 548308BDBM548308(WO2022093856, Example 1-5)
Affinity DataIC50: 1.14E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666715BDBM50666715(CHEMBL6175097)
Affinity DataIC50: 1.52E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666711BDBM50666711(CHEMBL6177605)
Affinity DataIC50: 1.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666712BDBM50666712(CHEMBL6171558)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652864BDBM652864(US20240059703, Example 1-17 | 1-(6-(4-(5-methyl-1H...)
Affinity DataIC50: 3.83E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652855BDBM652855((P)-7,7-dimethyl-4-(5- methyl-1H-indazol-4-yl)- 2-...)
Affinity DataIC50: 7.46E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed