Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50023420
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663373BDBM50663373(CHEMBL562641)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663371BDBM50663371(CHEMBL6147328)
Affinity DataEC50:  3nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663373BDBM50663373(CHEMBL562641)
Affinity DataEC50:  14nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663371BDBM50663371(CHEMBL6147328)
Affinity DataEC50:  16nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663371BDBM50663371(CHEMBL6147328)
Affinity DataEC50:  18nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663372BDBM50663372(CHEMBL6167790)
Affinity DataEC50:  25nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663373BDBM50663373(CHEMBL562641)
Affinity DataEC50:  31nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663370BDBM50663370(CHEMBL6150931)
Affinity DataEC50:  34nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663373BDBM50663373(CHEMBL562641)
Affinity DataEC50:  36nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663368BDBM50663368(CHEMBL6164583)
Affinity DataEC50:  38nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663361BDBM50663361(CHEMBL6170779)
Affinity DataEC50:  41nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663372BDBM50663372(CHEMBL6167790)
Affinity DataEC50:  51nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663361BDBM50663361(CHEMBL6170779)
Affinity DataEC50:  57nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663368BDBM50663368(CHEMBL6164583)
Affinity DataEC50:  72nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663368BDBM50663368(CHEMBL6164583)
Affinity DataEC50:  74nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663361BDBM50663361(CHEMBL6170779)
Affinity DataEC50:  81nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663360BDBM50663360(CHEMBL6145950)
Affinity DataEC50:  88nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663369BDBM50663369(CHEMBL6144737)
Affinity DataEC50:  102nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663366BDBM50663366(CHEMBL6173974)
Affinity DataEC50:  110nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663372BDBM50663372(CHEMBL6167790)
Affinity DataEC50:  120nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  130nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663369BDBM50663369(CHEMBL6144737)
Affinity DataEC50:  133nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583019BDBM50583019(CHEMBL5081008)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of glycine and L-glutamate by two-electrode ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663360BDBM50663360(CHEMBL6145950)
Affinity DataEC50:  150nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23167BDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Affinity DataEC50:  170nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663366BDBM50663366(CHEMBL6173974)
Affinity DataEC50:  180nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663360BDBM50663360(CHEMBL6145950)
Affinity DataEC50:  200nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23167BDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663370BDBM50663370(CHEMBL6150931)
Affinity DataEC50:  210nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663362BDBM50663362(CHEMBL6164031)
Affinity DataEC50:  230nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663370BDBM50663370(CHEMBL6150931)
Affinity DataEC50:  240nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663366BDBM50663366(CHEMBL6173974)
Affinity DataEC50:  290nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663375BDBM50663375(CHEMBL6159574)
Affinity DataEC50:  300nMAssay Description:Agonist activity at GluN1/GluN2D (unknown origin) expressed in xenopus laevis oocytes by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663369BDBM50663369(CHEMBL6144737)
Affinity DataEC50:  303nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663375BDBM50663375(CHEMBL6159574)
Affinity DataEC50:  320nMAssay Description:Agonist activity at GluN1/GluN2C (unknown origin) expressed in xenopus laevis oocytes by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663375BDBM50663375(CHEMBL6159574)
Affinity DataEC50:  400nMAssay Description:Agonist activity at GluN1/GluN2B (unknown origin) expressed in xenopus laevis oocytes by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583019BDBM50583019(CHEMBL5081008)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of glycine and L-glutamate by two-electrode ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663359BDBM50663359(CHEMBL6173261)
Affinity DataEC50:  640nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663365BDBM50663365(CHEMBL6168571)
Affinity DataEC50:  660nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23167BDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Affinity DataEC50:  670nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663367BDBM50663367(CHEMBL6166978)
Affinity DataEC50:  740nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663362BDBM50663362(CHEMBL6164031)
Affinity DataEC50:  880nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663363BDBM50663363(CHEMBL6143894)
Affinity DataEC50:  930nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663362BDBM50663362(CHEMBL6164031)
Affinity DataEC50:  980nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  1.00E+3nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663367BDBM50663367(CHEMBL6166978)
Affinity DataEC50:  1.07E+3nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583019BDBM50583019(CHEMBL5081008)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of glycine and L-glutamate by two-electrode ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23167BDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Affinity DataEC50:  1.13E+3nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
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