Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50023112
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK3(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463838BDBM50463838(CHEMBL4238926)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.840nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507816BDBM50507816(Bms-986165 | Deucravacitinib | US12351572, Example...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 246868BDBM246868({1-{1-[3-Fluoro-2- (trifluoromethyl) isonicotinoyl...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355501BDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 150200BDBM150200(US8980905, 108 | US9637499, Compound 108)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 150200BDBM150200(US8980905, 108 | US9637499, Compound 108)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355501BDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463838BDBM50463838(CHEMBL4238926)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463838BDBM50463838(CHEMBL4238926)
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463838BDBM50463838(CHEMBL4238926)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659305BDBM50659305(CHEMBL6143080)
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659305BDBM50659305(CHEMBL6143080)
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAryl hydrocarbon receptor(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603566BDBM50603566(TAPINAROF | Tapinarof | Benvitimod | Vtama | Wbi-1...)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 322155BDBM322155(US11311541, Example SLx-2119 | US10696660, SLx-211...)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659303BDBM50659303(CHEMBL6160881)
Affinity DataIC50: 74nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659303BDBM50659303(CHEMBL6160881)
Affinity DataIC50: 74nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439622BDBM50439622(CHEMBL2419346 | US10035797, Compound 111 | US96309...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439622BDBM50439622(CHEMBL2419346 | US10035797, Compound 111 | US96309...)
Affinity DataIC50: 103nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 322155BDBM322155(US11311541, Example SLx-2119 | US10696660, SLx-211...)
Affinity DataIC50: 105nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659304BDBM50659304(Mufemilast | HEMAY-005 | HEMAY005)
Affinity DataIC50: 114nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed