Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50023411
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663290BDBM50663290(CHEMBL6163756)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant Escherichia coli DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photometric assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Escherichia coli DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photometric assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663291BDBM50663291(CHEMBL6173068)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant Escherichia coli DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photometric assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663290BDBM50663290(CHEMBL6163756)
Affinity DataIC50: 18nMAssay Description:Inhibition of Plasmodium falciparum DXR extracted from Escherichia coli using DXP as substrate by NADPH consumption based photometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 21nMAssay Description:Inhibition of Plasmodium falciparum DXR extracted from Escherichia coli using DXP as substrate by NADPH consumption based photometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663291BDBM50663291(CHEMBL6173068)
Affinity DataIC50: 48nMAssay Description:Inhibition of Plasmodium falciparum DXR extracted from Escherichia coli using DXP as substrate by NADPH consumption based photometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663292BDBM50663292(CHEMBL6163485)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant Escherichia coli DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photometric assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663290BDBM50663290(CHEMBL6163756)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photom...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663291BDBM50663291(CHEMBL6173068)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photom...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663292BDBM50663292(CHEMBL6163485)
Affinity DataIC50: 97nMAssay Description:Inhibition of Plasmodium falciparum DXR extracted from Escherichia coli using DXP as substrate by NADPH consumption based photometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663293BDBM50663293(CHEMBL6167397)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photom...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663292BDBM50663292(CHEMBL6163485)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DXR extracted from Escherichia coli M15 using DXP as substrate by NADPH consumption based photom...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed