Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50023409
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689215BDBM689215(US20240254114, Example 17 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689216BDBM689216(US20240254114, Example 18 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689213BDBM689213(US20240254114, Example 15 | 6-((3-(2,2-difluoroeth...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689214BDBM689214(US20240254114, Example 16 | 6-((3-(2,2-difluoroeth...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689212BDBM689212(US20240254114, Example 14 | 6-((5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689227BDBM689227(US20240254114, Example 39 | 5-[[3-(2,2-difluoroeth...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689211BDBM689211(US20240254114, Example 13 | 6-((5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689228BDBM689228(US20240254114, Example 40 | 5-[[5-chloro-3-(2,2- d...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689217BDBM689217(US20240254114, Example 19 | 6-((5-chloro-3-(2,2- d...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689218BDBM689218(US20240254114, Example 20 | 6-((5-chloro-3-(2,2- d...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689219BDBM689219(US20240254114, Example 31 | 5-[[5-chloro-3-(2,2,2-...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 689221BDBM689221(US20240254114, Example 33 | 5-[[5-chloro-3-(2,2- d...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed