Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50023401
Affinity DataIC50: 0.740nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.90nMAssay Description:Inhibition of TRKC (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of TRKC (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of TRKC (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 25nMAssay Description:Inhibition of TRKC (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by HTRF ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of C-terminal 6-his tagged human TRKA (440 to 796 residues) expressed in Sf21 cells incubated for 2 hrs in presence of ATP by lanthascreen...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.98E+3nMAssay Description:Inhibition of wild type TRKA (unknown origin) using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min...More data for this Ligand-Target Pair
Ligand Info




3D Structure (crystal)






























