Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50022936
Affinity DataKd: <0.00100nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.0200nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.0310nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.0400nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.0500nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.160nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.240nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.260nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.840nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.940nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding affinity to inactive GDP bound KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Binding affinity to active GTP bound KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataKd: 8.80nMAssay Description:Binding affinity to wildtype KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Inhibition of wildtype KRAS (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 391nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 671nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 704nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity to TRKA (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity to Aurora B (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
