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Found
123
Enz. Inhib. hit(s) with all data for entry = 50022934
Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50362846
(CHEMBL1940394)
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Affinity Data
IC50: 10nM
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50321718
(2-(2,4-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)
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Affinity Data
IC50: 10nM
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16452
((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
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Affinity Data
IC50: 10nM
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In Depth
Date in BDB:
6/4/2026
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3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16314
(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
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Affinity Data
IC50: 14nM
More data for this Ligand-Target Pair
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DrugBank
KEGG
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Date in BDB:
6/4/2026
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3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50394657
(CHEMBL270067)
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Affinity Data
IC50: 20nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656340
(Minalrestat | WAY-ARI-509)
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Affinity Data
IC50: 20nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50321715
(2-(2,5-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)
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IC50: 20nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50049730
(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
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Affinity Data
IC50: 20nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50321716
(2-(3,4-dimethoxyphenylimino)-7-hydroxy-N-(6-methyl...)
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IC50: 30nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50375584
(CHEMBL429432)
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Affinity Data
IC50: 50nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16314
(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
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Affinity Data
IC50: 50nM
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Date in BDB:
6/4/2026
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3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50029207
(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
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IC50: 80nM
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Date in BDB:
6/4/2026
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PDB
3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM200221
(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)
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IC50: 80nM
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Date in BDB:
6/4/2026
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3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16512
((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
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IC50: 80nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50362841
(CHEMBL1940399)
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IC50: 100nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50103504
(Sulindac | CHEBI:9352 | Clinoril)
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IC50: 210nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM7460
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
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IC50: 230nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM7461
(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
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IC50: 290nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50241453
(gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...)
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IC50: 290nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656341
(CHEMBL6133621)
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Affinity Data
IC50: 300nM
More data for this Ligand-Target Pair
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50540070
(CHEMBL366760)
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IC50: 300nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50236240
(Epiandrosterone | epi-andosterone | 5alpha-androst...)
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IC50: 320nM
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PC cid
PC sid
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50049730
(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
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Affinity Data
IC50: 330nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50103504
(Sulindac | CHEBI:9352 | Clinoril)
Copy SMILES
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Affinity Data
IC50: 350nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656345
(CHEMBL6150275)
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Affinity Data
IC50: 370nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50025405
(10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenant...)
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IC50: 390nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50056938
(NSC-66209 | cid_72721 | CHEMBL175266 | 2,6,7-Trihy...)
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IC50: 400nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50375561
(CHEMBL407717)
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IC50: 440nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656342
(CHEMBL6152189)
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Affinity Data
IC50: 450nM
More data for this Ligand-Target Pair
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50388495
(CHEMBL2057301)
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IC50: 500nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50321717
(7-hydroxy-2-(4-methoxyphenylimino)-N-(pyridin-2-yl...)
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IC50: 500nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50362835
(CHEMBL1940400)
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IC50: 500nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50042949
((E)-3-(3,4-Dihydroxy-phenyl)-1-(2,4-dihydroxy-phen...)
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IC50: 500nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656348
(CHEMBL6103402)
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Affinity Data
IC50: 500nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM19459
(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
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IC50: 550nM
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6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16312
(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
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IC50: 550nM
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Date in BDB:
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656344
(CHEMBL4160626)
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Affinity Data
IC50: 570nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50029207
(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
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IC50: 570nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50175892
(Maslinicacid | 2alpha,3beta-dihydroxy-12-oleanen-2...)
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IC50: 600nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM15236
(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
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IC50: 610nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM16452
((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Copy SMILES
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Affinity Data
IC50: 620nM
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Date in BDB:
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3D Structure (crystal)
Copy reaction URL
Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656340
(Minalrestat | WAY-ARI-509)
Copy SMILES
Affinity Data
IC50: 740nM
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656350
(CHEMBL6170828)
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Affinity Data
IC50: 760nM
More data for this Ligand-Target Pair
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Date in BDB:
6/4/2026
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM17636
(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
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Affinity Data
IC50: 760nM
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Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656346
(CHEMBL486954)
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Affinity Data
IC50: 780nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50241827
(CHEMBL4071421)
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Affinity Data
IC50: 800nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Aldo-keto reductase family 1 member B1
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656343
(CHEMBL376915)
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Affinity Data
IC50: 810nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Copy reaction URL
Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656347
(CHEMBL6164391)
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Affinity Data
IC50: 810nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Copy reaction URL
Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50656349
(CHEMBL6160316)
Copy SMILES
Affinity Data
IC50: 830nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Copy reaction URL
Target
Aldo-keto reductase family 1 member B10
(Human)
University of Messina
Curated by
ChEMBL
Ligand
BDBM50346601
(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
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Affinity Data
IC50: 900nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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