Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50023046
Affinity DataKi: 0.110nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of CDK1/Cyclin A2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK6/Cyclin D2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 451nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 524nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 624nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 813nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 882nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair

3D Structure (crystal)















