Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50022798
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654417BDBM50654417(CHEMBL6102198)
Affinity DataIC50: 0.25nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654420BDBM50654420(CHEMBL5222042)
Affinity DataIC50: 1nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654418BDBM50654418(CHEMBL6102303)
Affinity DataKd:  1.70nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654417BDBM50654417(CHEMBL6102198)
Affinity DataIC50: 7.10nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654419BDBM50654419(CHEMBL6120478)
Affinity DataIC50: 7.20nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536383BDBM50536383(CHEMBL4584526)
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654421BDBM50654421(CHEMBL6142288)
Affinity DataIC50: 9.80nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654411BDBM50654411(CHEMBL6144042)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654410BDBM50654410(CHEMBL6143180)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654409BDBM50654409(CHEMBL6143296)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654408BDBM50654408(CHEMBL6145330)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654415BDBM50654415(CHEMBL6132854)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654414BDBM50654414(CHEMBL6092069)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654413BDBM50654413(CHEMBL6145218)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654412BDBM50654412(CHEMBL6091754)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654416BDBM50654416(CHEMBL6144882)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654407BDBM50654407(CHEMBL6103411)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed