Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50022930
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656330BDBM50656330(CHEMBL6163134)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 172038BDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446376BDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281297BDBM50281297(CHEMBL4170114)
Affinity DataIC50: 8nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300032BDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 13nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300032BDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 13nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300028BDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataKi:  16nMAssay Description:Binding affinity to G9a (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613160BDBM50613160(CHEMBL5279012)
Affinity DataIC50: 27nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608123BDBM50608123(CHEMBL5281928)
Affinity DataIC50: 67nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1/EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498655BDBM50498655(CHEMBL1895209)
Affinity DataIC50: 100nMAssay Description:Inhibition of G9a/GLP in human MDA-MB-231 cells assessed as reduction in H3K9 dimethylation incubated for 3 days by Western blotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656329BDBM50656329(CHEMBL6161933)
Affinity DataIC50: 126nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281297BDBM50281297(CHEMBL4170114)
Affinity DataIC50: 382nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300028BDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 700nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300028BDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656331BDBM50656331(CHEMBL120235)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526221BDBM50526221(CHEMBL4454542)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353132BDBM50353132(CHEMBL1829305)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346553BDBM50346553(CHEMBL1797937)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346553BDBM50346553(CHEMBL1797937)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353131BDBM50353131(CHEMBL1829304)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075052BDBM50075052(CHEMBL3414617)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202440BDBM50202440(CHEMBL3933828)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1/EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569835BDBM50569835(CHEMBL4850917)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of G9a/GLP in human MDA-MB-231 cells assessed as reduction in H3K9 dimethylation incubated for 3 days by Western blotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315537BDBM50315537(chaetocin | CHEMBL1089316)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656328BDBM50656328(CHEMBL6171235)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569835BDBM50569835(CHEMBL4850917)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of HDAC in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030260BDBM50030260(CHEMBL3343657)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498655BDBM50498655(CHEMBL1895209)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 5.09E+5nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed