Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022795
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654388BDBM50654388(CHEMBL6082979)
Affinity DataIC50: 21nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654387BDBM50654387(CHEMBL6143060)
Affinity DataIC50: 24nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654389BDBM50654389(CHEMBL6103521)
Affinity DataIC50: 25nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654386BDBM50654386(CHEMBL6147570)
Affinity DataIC50: 30nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProthrombin(Human)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117680BDBM50117680(CHEMBL3613792)
Affinity DataKi:  57nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654385BDBM50654385(CHEMBL6114864)
Affinity DataIC50: 230nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProthrombin(Human)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117692BDBM50117692(CHEMBL3613791)
Affinity DataKi:  310nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCaspase-6(Human)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117678BDBM50117678(CHEMBL3613794)
Affinity DataKd:  470nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCaspase-6(Human)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117679BDBM50117679(CHEMBL3613793)
Affinity DataKd:  2.90E+3nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
East China Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654384BDBM50654384(CHEMBL6102427)
Affinity DataIC50: 2.82E+4nMAssay Description:Transactivation of mouse PPARdelta by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed