Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022912
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572159BDBM50572159(CHEMBL1489870 | US20240317691, Compound Inhibitor-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human N-terminal his-6 tagged 15-LOX-2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572160BDBM50572160(CHEMBL1452107)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human N-terminal his-6 tagged 15-LOX-2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656023BDBM50656023(CHEMBL1324227)
Affinity DataKi:  1.51E+4nMAssay Description:Mixed type inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells assessed as inhibition constant by lineweaver-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656022BDBM50656022(CHEMBL6147481)
Affinity DataKi:  1.64E+4nMAssay Description:Mixed type inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells assessed as inhibition constant by lineweaver-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656023BDBM50656023(CHEMBL1324227)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells using arachidonic acid as substrate preincubated for 2 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656022BDBM50656022(CHEMBL6147481)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells using arachidonic acid as substrate preincubated for 2 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656024BDBM50656024((HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE)
Affinity DataKi:  9.20E+4nMAssay Description:Binding affinity to human his-tagged 15-LOX-2 expressed in Rossetta 2 DE3 assessed as inhibition constant using arachidonic acid as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)