Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50022731
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 41nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641843BDBM50641843(CHEMBL5574586)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653668BDBM50653668(CHEMBL6078202)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653669BDBM50653669(CHEMBL6143227)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653664BDBM50653664(CHEMBL6092055)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653661BDBM50653661(CHEMBL6114885)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653674BDBM50653674(CHEMBL6092033)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653686BDBM50653686(CHEMBL6142651)
Affinity DataIC50: 77nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653685BDBM50653685(CHEMBL6132746)
Affinity DataIC50: 84nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653676BDBM50653676(CHEMBL6078556)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653666BDBM50653666(CHEMBL6087332)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653662BDBM50653662(CHEMBL6078158)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653680BDBM50653680(CHEMBL6101866)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653671BDBM50653671(CHEMBL6078010)
Affinity DataIC50: 99nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653663BDBM50653663(CHEMBL6150700)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653678BDBM50653678(CHEMBL6078251)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653679BDBM50653679(CHEMBL6102946)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653684BDBM50653684(CHEMBL1404812)
Affinity DataIC50: 121nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641842BDBM50641842(CHEMBL5571237)
Affinity DataIC50: 122nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653677BDBM50653677(CHEMBL6102686)
Affinity DataIC50: 123nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653683BDBM50653683(CHEMBL1593862)
Affinity DataIC50: 125nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653673BDBM50653673(CHEMBL6141603)
Affinity DataIC50: 129nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653667BDBM50653667(CHEMBL6141804)
Affinity DataIC50: 129nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653675BDBM50653675(CHEMBL6144152)
Affinity DataIC50: 144nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653681BDBM50653681(CHEMBL6103048)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653682BDBM50653682(CHEMBL6101971)
Affinity DataIC50: 152nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653672BDBM50653672(CHEMBL6133759)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653670BDBM50653670(CHEMBL6120879)
Affinity DataIC50: 188nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Misr University for Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653665BDBM50653665(CHEMBL6141605)
Affinity DataIC50: 196nMAssay Description:Antagonist activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production by cell based assay in presence of 50% human serumMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed