Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50022718
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16173BDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653485BDBM50653485(CHEMBL6120373)
Affinity DataIC50: 1.14E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653486BDBM50653486(CHEMBL6144838)
Affinity DataIC50: 1.47E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653487BDBM50653487(CHEMBL6114854)
Affinity DataIC50: 2.80E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653488BDBM50653488(CHEMBL6103308)
Affinity DataIC50: 3.57E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653489BDBM50653489(CHEMBL6120518)
Affinity DataIC50: 4.16E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653490BDBM50653490(CHEMBL6087334)
Affinity DataIC50: 4.93E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653492BDBM50653492(CHEMBL6082953)
Affinity DataIC50: 5.16E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653491BDBM50653491(CHEMBL6148878)
Affinity DataIC50: 6.20E+5nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653493BDBM50653493(CHEMBL6144727)
Affinity DataIC50: 6.71E+5nMAssay Description:Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653494BDBM50653494(CHEMBL6102811)
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed