Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50022716
Affinity DataKi: 0.0400nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.100nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.130nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.140nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.170nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.200nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.200nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.200nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.210nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.25nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.25nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.260nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.280nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.300nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.350nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.380nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.400nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta-lactamase assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.410nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.5nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.5nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.5nMAssay Description:Inhibition of 14-3-3sigma (unknown origin) assessed as reduction in 14-3-3sigma- mediated increase in MMP1 mRNA by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.530nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.600nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.600nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.650nMAssay Description:Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditionsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.700nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.700nMAssay Description:Agonist activity at human PPAR delta by cell based reporter assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.800nMAssay Description:Agonist activity at human PPAR delta by cell based reporter assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.820nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.900nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Agonist activity at human PPAR delta by cell based cotransfection assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.20nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.30nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.40nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.40nMAssay Description:Inhibition of human ERG by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.40nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.60nMAssay Description:Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditionsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2.10nMAssay Description:Inhibition of farnesyl transferase in NIH3T3 cell based assay under reducing (+DTT) conditionsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.20nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2.20nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2.80nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2.90nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 4nMAssay Description:Inhibition of AXL (unknown origin) by cell based assayMore data for this Ligand-Target Pair
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