Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50022871
Affinity DataKd: 0.240nMAssay Description:Binding affinity to HIF-2alpha (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at OX1 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at OX2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of renin (unknown origin) using Arg-Glu(EDANS)-lle-His-Pro-Phe-His-Leu-Val-lle-His-Thr-Lys(dabcyl)-Arg as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Enamine Ltd.
Curated by ChEMBL
Enamine Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to HIF-2alpha (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 6nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of SARS-CoV-2 main protease extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to HIF-2alpha (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 11nMAssay Description:Antagonist activity at OX2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to HIF-2alpha (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-Gly-Lys (Ac)-AMC as substrate measured for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 52nMAssay Description:Binding affinity to HIF-2alpha (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 60nMAssay Description:Antagonist activity at OX1 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 182nMAssay Description:Inhibition of SARS-CoV-2 main protease extracted from Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 450nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
