Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50022870
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655397BDBM50655397(CHEMBL6142590)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655388BDBM50655388(CHEMBL6143889)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655387BDBM50655387(CHEMBL6102394)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655397BDBM50655397(CHEMBL6142590)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50380399BDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655389BDBM50655389(CHEMBL6146648)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655391BDBM50655391(CHEMBL6143761)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655392BDBM50655392(CHEMBL6102723)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655387BDBM50655387(CHEMBL6102394)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655393BDBM50655393(CHEMBL6149703)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655391BDBM50655391(CHEMBL6143761)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655392BDBM50655392(CHEMBL6102723)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655394BDBM50655394(CHEMBL6146485)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655390BDBM50655390(CHEMBL6142255)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655388BDBM50655388(CHEMBL6143889)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655386BDBM50655386(CHEMBL6146959)
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655395BDBM50655395(CHEMBL6144448)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655395BDBM50655395(CHEMBL6144448)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655396BDBM50655396(CHEMBL6091978)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655390BDBM50655390(CHEMBL6142255)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant Human HDAC3/NCOR2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655386BDBM50655386(CHEMBL6146959)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655393BDBM50655393(CHEMBL6149703)
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655394BDBM50655394(CHEMBL6146485)
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655396BDBM50655396(CHEMBL6091978)
Affinity DataIC50: 108nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 165nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 299nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 725nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655390BDBM50655390(CHEMBL6142255)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655387BDBM50655387(CHEMBL6102394)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655391BDBM50655391(CHEMBL6143761)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655393BDBM50655393(CHEMBL6149703)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant HDAC11 using Boc-Lys(trifluoroacetyl)-AMC) as fluorogenic substrate incubated for 90 mins by fluorescence based analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655397BDBM50655397(CHEMBL6142590)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655386BDBM50655386(CHEMBL6146959)
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655398BDBM50655398(CHEMBL6133873)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655396BDBM50655396(CHEMBL6091978)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655388BDBM50655388(CHEMBL6143889)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655394BDBM50655394(CHEMBL6146485)
Affinity DataIC50: 5.41E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as fluorogenic substrate incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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