Report error Found 152 Enz. Inhib. hit(s) with all data for entry = 50022868
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataKd: <1nMAssay Description:Binding affinity to N-terminal his 6 tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells assessed as dissoci...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD2 BD2 (347 to 455 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRDT BD2 extracted from Escherichia coli BL21 (DE3) cells using biotinylated tetraacetylated Hist...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of JAK2 in human A-431 cells assessed as reduction in IL-6-induced STAT3 phosphorylation preincubated for 1 hr followed by IL-6-stimulatio...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FLAG-tagged SMYD2 methylation co-transfected in human U2OS cells assessed as decrease in levels of p53 by measured after 15 hrs by cell...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of JAK1/JAK2 in human A-431 cells assessed as reduction in IL-6-induced STAT3 phosphorylation at 1 uM preincubated for 1 hr followed by IL...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain testis-specific protein(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRDT BD2 extracted from Escherichia coli BL21 (DE3) cells using biotinylated tetraacetylated Hist...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD2 BD2 (347 to 455 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info





























