Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50022768
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208517BDBM50208517(KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316806BDBM50316806((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654075BDBM50654075(CHEMBL189326)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654077BDBM50654077(CHEMBL6133392)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654081BDBM50654081(ARTEMISIDE)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654080BDBM50654080(Artemifone | Artemisone | BAY 44-9585 | BAY-449585)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654078BDBM50654078(CHEMBL3393648)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654076BDBM50654076(CHEMBL3885317)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654079BDBM50654079(Basifungin | Basifungine | Basifungina | Aureobasi...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266967BDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654082BDBM50654082(CHEMBL6141786)
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed