Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50022712
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531288BDBM531288(US11208399, Example 47)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531253BDBM531253(US11208399, Example 12)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531220BDBM531220(US11208399, Example 1 | (R)-2-(6-((1-Ethylpiperidi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531230BDBM531230(US11208399, Example 6)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531286BDBM531286(US11208399, Example 45)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531230BDBM531230(US11208399, Example 6)
Affinity DataIC50: 2.10nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531220BDBM531220(US11208399, Example 1 | (R)-2-(6-((1-Ethylpiperidi...)
Affinity DataIC50: 2.5nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531323BDBM531323(US11208399, Example 74)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531288BDBM531288(US11208399, Example 47)
Affinity DataIC50: 5.80nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531220BDBM531220(US11208399, Example 1 | (R)-2-(6-((1-Ethylpiperidi...)
Affinity DataIC50: 7nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531253BDBM531253(US11208399, Example 12)
Affinity DataIC50: 7.70nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531253BDBM531253(US11208399, Example 12)
Affinity DataIC50: 8nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531288BDBM531288(US11208399, Example 47)
Affinity DataIC50: 8nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISA in presence of 8 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531230BDBM531230(US11208399, Example 6)
Affinity DataIC50: 9nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531286BDBM531286(US11208399, Example 45)
Affinity DataIC50: 15nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531283BDBM531283(US11208399, Example 42)
Affinity DataIC50: 26nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531323BDBM531323(US11208399, Example 74)
Affinity DataIC50: 28nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531258BDBM531258(US11208399, Example 17)
Affinity DataIC50: 28nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531283BDBM531283(US11208399, Example 42)
Affinity DataIC50: 170nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531266BDBM531266(US11208399, Example 25)
Affinity DataIC50: 190nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531268BDBM531268(US11208399, Example 27)
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531258BDBM531258(US11208399, Example 17)
Affinity DataIC50: 370nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531277BDBM531277(US11208399, Example 36)
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531285BDBM531285(US11208399, Example 44)
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653319BDBM50653319(CHEMBL6102916)
Affinity DataIC50: 430nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653319BDBM50653319(CHEMBL6102916)
Affinity DataIC50: 1.13E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653320BDBM50653320(CHEMBL6078107)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653318BDBM50653318(CHEMBL6083156)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531277BDBM531277(US11208399, Example 36)
Affinity DataIC50: 2.90E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653321BDBM50653321(CHEMBL6145268)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653318BDBM50653318(CHEMBL6083156)
Affinity DataIC50: 1.32E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653322BDBM50653322(CHEMBL6091785)
Affinity DataIC50: 1.57E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653321BDBM50653321(CHEMBL6145268)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISA in presence of 8 uM ATPMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPyrin(Homo sapiens)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531220BDBM531220(US11208399, Example 1 | (R)-2-(6-((1-Ethylpiperidi...)
Affinity DataIC50: 3.30E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531266BDBM531266(US11208399, Example 25)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653318BDBM50653318(CHEMBL6083156)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653319BDBM50653319(CHEMBL6102916)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531286BDBM531286(US11208399, Example 45)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531220BDBM531220(US11208399, Example 1 | (R)-2-(6-((1-Ethylpiperidi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531285BDBM531285(US11208399, Example 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653320BDBM50653320(CHEMBL6078107)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 531268BDBM531268(US11208399, Example 27)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed