Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50022711
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561039BDBM50561039(CHEMBL4749355 | US11420984, Example 23)
Affinity DataIC50: 3nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561039BDBM50561039(CHEMBL4749355 | US11420984, Example 23)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561038BDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50: 7nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561038BDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653288BDBM50653288(CHEMBL6082888)
Affinity DataIC50: 39nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568475BDBM568475(US11420984, Example 25)
Affinity DataIC50: 64nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577458BDBM50577458(CHEMBL4858437)
Affinity DataIC50: 70nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653288BDBM50653288(CHEMBL6082888)
Affinity DataIC50: 81nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577458BDBM50577458(CHEMBL4858437)
Affinity DataIC50: 135nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568475BDBM568475(US11420984, Example 25)
Affinity DataIC50: 154nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568461BDBM568461(US11420984, Example 11)
Affinity DataIC50: 205nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653317BDBM50653317(CHEMBL6149956)
Affinity DataIC50: 266nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568464BDBM568464(US11420984, Example 14)
Affinity DataIC50: 311nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561043BDBM50561043(CHEMBL4746323 | US11420984, Example 9)
Affinity DataIC50: 328nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568463BDBM568463(US11420984, Example 13)
Affinity DataIC50: 447nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350311BDBM50350311(CHEMBL1812661)
Affinity DataIC50: 473nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350311BDBM50350311(CHEMBL1812661)
Affinity DataIC50: 520nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568458BDBM568458(US11420984, Example 8)
Affinity DataIC50: 612nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568462BDBM568462(US11420984, Example 12)
Affinity DataIC50: 768nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568479BDBM568479(US11420984, Example 29)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed