Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50023031
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 38019BDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataKd:  17nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658082BDBM50658082(CHEMBL6168472)
Affinity DataKd:  200nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 38019BDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 210nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658075BDBM50658075(CHEMBL6149976)
Affinity DataKd:  740nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658082BDBM50658082(CHEMBL6168472)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658075BDBM50658075(CHEMBL6149976)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658074BDBM50658074(CHEMBL6146711)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658074BDBM50658074(CHEMBL6146711)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658080BDBM50658080(CHEMBL6152807)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to 4PCP WAVE chip-immobilized His-tagged full-length recombinant SHP2 (unknown origin) assessed as equilibrium dissociation rate by ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658080BDBM50658080(CHEMBL6152807)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658078BDBM50658078(CHEMBL6145428)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658083BDBM50658083(CHEMBL6168830)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658079BDBM50658079(CHEMBL6143055)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658084BDBM50658084(CHEMBL6145961)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658081BDBM50658081(CHEMBL6160949)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658076BDBM50658076(CHEMBL6163825)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658077BDBM50658077(CHEMBL6147614)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of His-tagged full-length recombinant SHP2 (unknown origin) using bisphosphorylated IRS-1 peptide/DiFMUP as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed