Report error Found 116 Enz. Inhib. hit(s) with all data for entry = 50022862
Affinity DataKd: <0.200nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 0.540nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 0.550nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 36nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 69nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of GSK-3beta (unknown origin) assessed as decrease in tau phosphorylation by high content cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell based calcium assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 103nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 130nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 153nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 180nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 183nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 210nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 240nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR incubated for 24 hrs by cell-based luciferase t...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 297nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 300nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 320nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 340nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 390nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR incubated for 24 hrs by cell-based luciferase t...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 400nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 400nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 410nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 415nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 420nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 440nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 460nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction expressed in Escherichia coli BL21 codon plus cells using FITC-beta-DEETGEF-OH ...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 500nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell based calcium assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 560nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 561nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 643nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 740nMAssay Description:Inhibition of GSK-3beta (unknown origin) assessed as decrease in tau phosphorylation by high content cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
