Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50023096
Affinity DataEC50: 8nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human Primary lung fibroblast cells pre-incubated for 1 hr followed by LPA stimulation and meas...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 12nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 12nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Antagonist activity at human wild-type LPA1 receptor expressed in HEK293 cells assessed as internalization incubated for 30 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 21nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 31nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 32nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 34nMAssay Description:Antagonist activity at LPA1 receptor in human TWNT-4 cells pre-incubated for 1 hr followed by LPA stimulation and measured after 30 min in presence o...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 37nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 41nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 45nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 51nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]LPA from human LPA1 receptor overexpressed in CHO cell membrane assessed as inhibition constant incubated for 90 min by competiti...More data for this Ligand-Target Pair
Affinity DataEC50: 77nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 81nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 83nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 108nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 109nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 109nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 122nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 124nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 186nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 237nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 417nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 522nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 546nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 576nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 612nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 754nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 890nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 893nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 953nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 1.35E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 1.37E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 1.55E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 2.38E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 5.25E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Affinity DataEC50: 7.53E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 7.92E+3nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at LPA1 receptor in serum starved human TWNT-4 cells assessed as nuclear translocation pre-incubated for 1 hr followed by LPA sti...More data for this Ligand-Target Pair
Ligand Info
TargetSolute carrier organic anion transporter family member 1B1(Human)
Gilead Sciences Inc.
Curated by ChEMBL
Gilead Sciences Inc.
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of OATPB1P1 in human hepatocyte by LC-MS analysisMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Human)
Gilead Sciences Inc.
Curated by ChEMBL
Gilead Sciences Inc.
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of OATPB1P3 in human hepatocyte by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of BSEP in human hepatocyte by LC-MS analysisMore data for this Ligand-Target Pair
