Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50022861
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655255BDBM50655255(CHEMBL6162105)
Affinity DataKd:  270nMAssay Description:Inhibition of NanoLuc-PKN2 (ser646-cys984)(unknown origin) expressed in HEK293 cells by cell-based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655255BDBM50655255(CHEMBL6162105)
Affinity DataKd:  370nMAssay Description:Inhibition of NanoLuc-PKN2 (ser646-cys984)(unknown origin) expressed in HEK293 cells by cell-based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655252BDBM50655252(CHEMBL6144552)
Affinity DataKd:  770nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655251BDBM50655251(CHEMBL6150062)
Affinity DataKd:  810nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655248BDBM50655248(CHEMBL6120587)
Affinity DataKd:  1.22E+3nMAssay Description:Antagonist activity at OX1R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655250BDBM50655250(CHEMBL6161953)
Affinity DataKd:  1.23E+3nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655249BDBM50655249(CHEMBL6101924)
Affinity DataKd:  1.40E+3nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655254BDBM50655254(CHEMBL6145785)
Affinity DataKd:  1.52E+3nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655253BDBM50655253(CHEMBL6151523)
Affinity DataKd:  2.19E+3nMAssay Description:Antagonist activity at OX2R (unknown origin) by cell-based calcium assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655256BDBM50655256(CHEMBL6143043)
Affinity DataIC50: 2.53E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR incubated for 24 hrs by cell-based luciferase t...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655264BDBM50655264(CHEMBL6146368)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655265BDBM50655265(CHEMBL5267405)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655263BDBM50655263(CHEMBL6151868)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655256BDBM50655256(CHEMBL6143043)
Affinity DataKd:  4.41E+3nMAssay Description:Inhibition of NanoLuc-PKN2 (ser646-cys984)(unknown origin) expressed in HEK293 cells by cell-based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655260BDBM50655260(CHEMBL6147560)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655258BDBM50655258(Mitoquinone | Mitoquinone cation | Mitoquinone ion)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of HPK1(unknown origin) assessed as inhibition of SLP76 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655255BDBM50655255(CHEMBL6162105)
Affinity DataKd:  5.21E+3nMAssay Description:Inhibition of NanoLuc-PKN2 (ser646-cys984)(unknown origin) expressed in HEK293 cells by cell-based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655258BDBM50655258(Mitoquinone | Mitoquinone cation | Mitoquinone ion)
Affinity DataKd:  6.60E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR incubated for 24 hrs by cell-based luciferase t...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655272BDBM50655272(CHEMBL6160592)
Affinity DataIC50: 8.05E+3nMAssay Description:Binding affinity to C-terminal His-tagged mouse recombinant SerpinA3n expressed in Escherichia coli BL21(DE3) pLysS cells assessed as dissociation co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655262BDBM50655262(CHEMBL6103433)
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655271BDBM50655271(CHEMBL3582496)
Affinity DataIC50: 8.94E+3nMAssay Description:Inhibition of full length Nano-luc fused EPHB3 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655268BDBM50655268(CHEMBL6133920)
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of full length Nano-luc fused EPHB3 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655270BDBM50655270(CHEMBL6152348)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of full length Nano-luc fused EPHB3 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655267BDBM50655267(CHEMBL6101816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655266BDBM50655266(CHEMBL6142904)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655269BDBM50655269(CHEMBL6120915)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Nano-luc fused EPHB3 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655257BDBM50655257(CHEMBL6150637)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HPK1(unknown origin) assessed as inhibition of SLP76 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655259BDBM50655259(CHEMBL6151538)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655261BDBM50655261(CHEMBL6134025)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655256BDBM50655256(CHEMBL6143043)
Affinity DataKd:  2.80E+4nMAssay Description:Inhibition of NanoLuc-PKN2 (ser646-cys984)(unknown origin) expressed in HEK293 cells in absence of tracer by cell-based NanoBRET target engagement as...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed