Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50022893
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655789BDBM50655789(CHEMBL6148843)
Affinity DataKi:  0.540nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038419BDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001028BDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338990BDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  4.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044725BDBM50044725(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-methyl-piperaz...)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655791BDBM50655791(CHEMBL6151311)
Affinity DataKi:  9.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655793BDBM50655793(CHEMBL6151058)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044725BDBM50044725(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-methyl-piperaz...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044725BDBM50044725(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-methyl-piperaz...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634776BDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009307BDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038419BDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655794BDBM50655794(CHEMBL6133341)
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655790BDBM50655790(CHEMBL6142780)
Affinity DataKi:  65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655792BDBM50655792(CHEMBL6142453)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655794BDBM50655794(CHEMBL6133341)
Affinity DataKi:  83nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338990BDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655788BDBM50655788(CHEMBL6152148)
Affinity DataKi:  96nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655792BDBM50655792(CHEMBL6142453)
Affinity DataKi:  108nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655785BDBM50655785(CHEMBL6141911)
Affinity DataKi:  114nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655790BDBM50655790(CHEMBL6142780)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009307BDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  124nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655788BDBM50655788(CHEMBL6152148)
Affinity DataKi:  134nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044725BDBM50044725(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-methyl-piperaz...)
Affinity DataKi:  204nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655785BDBM50655785(CHEMBL6141911)
Affinity DataKi:  232nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655787BDBM50655787(CHEMBL6163184)
Affinity DataKi:  268nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655787BDBM50655787(CHEMBL6163184)
Affinity DataKi:  323nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655786BDBM50655786(CHEMBL6102024)
Affinity DataKi: >1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001028BDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  1.47E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655786BDBM50655786(CHEMBL6102024)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655789BDBM50655789(CHEMBL6148843)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655793BDBM50655793(CHEMBL6151058)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655791BDBM50655791(CHEMBL6151311)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed