Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50022762
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236697BDBM50236697(L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-iso...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654010BDBM50654010(CHEMBL6147645)
Affinity DataKi:  2nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654011BDBM50654011(CHEMBL6133895)
Affinity DataKi:  2.90nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236697BDBM50236697(L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-iso...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654012BDBM50654012(CHEMBL6143072)
Affinity DataKi:  4.20nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654015BDBM50654015(CHEMBL6160173)
Affinity DataKi:  5.60nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228894BDBM50228894(CHEMBL312754)
Affinity DataKi:  6.30nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataKi:  7.60nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654014BDBM50654014(CHEMBL6150545)
Affinity DataKi:  11nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654013BDBM50654013(CHEMBL6134691)
Affinity DataKi:  23nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228894BDBM50228894(CHEMBL312754)
Affinity DataKi:  27nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654015BDBM50654015(CHEMBL6160173)
Affinity DataKi:  112nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654010BDBM50654010(CHEMBL6147645)
Affinity DataKi:  210nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654011BDBM50654011(CHEMBL6133895)
Affinity DataKi:  650nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654012BDBM50654012(CHEMBL6143072)
Affinity DataKi:  5.43E+3nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654014BDBM50654014(CHEMBL6150545)
Affinity DataKi:  5.57E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-1 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654013BDBM50654013(CHEMBL6134691)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of mTOR-mediated ribosomal protein S6 kinase phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetType-2 angiotensin II receptor(Human)
Universite de Lorraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed