Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50023514
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664649BDBM50664649(CHEMBL6171637)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20608BDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17292BDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20608BDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17292BDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664648BDBM50664648(CHEMBL6162124)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17292BDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20608BDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17292BDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 590nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 670nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664649BDBM50664649(CHEMBL6171637)
Affinity DataIC50: 1.14E+3nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20608BDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 1.19E+3nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664647BDBM50664647(CHEMBL6165317)
Affinity DataIC50: 9.30E+3nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664647BDBM50664647(CHEMBL6165317)
Affinity DataIC50: 2.96E+4nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78304BDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataIC50: 1.60E+5nMAssay Description:Antagonist activity at human ER-alpha transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78304BDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataIC50: 9.97E+5nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664648BDBM50664648(CHEMBL6162124)
Affinity DataIC50: 1.32E+6nMAssay Description:Antagonist activity at human ER-beta transfected in human HepG2 cells incubated for 24 hrs by 3xERE-driven luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed