Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50023015
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human HDAC2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HDAC2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC8 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human HDAC8 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human HDAC8 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657842BDBM50657842(CHEMBL6168062)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human SIRT2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human SIRT2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657843BDBM50657843(CHEMBL6150434)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human SIRT2 using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition for 240 mins and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed