Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022761
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001839BDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 30nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155773BDBM50155773(US9469597, 5 | CHEMBL3781751)
Affinity DataIC50: 30nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 512788BDBM512788(Isoforsy-thiaside)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241867BDBM50241867(((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 512788BDBM512788(Isoforsy-thiaside)
Affinity DataKd:  5.19E+3nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654009BDBM50654009(CHEMBL6159931)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269517BDBM50269517(Forsythiaside | CHEMBL504363 | forsythoside A)
Affinity DataIC50: 8.08E+3nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed