Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022759
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653970BDBM50653970(CHEMBL6149643)
Affinity DataIC50: 45nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653968BDBM50653968(CHEMBL6142819)
Affinity DataIC50: 109nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653967BDBM50653967(CHEMBL6148209)
Affinity DataIC50: 173nMAssay Description:Inhibition of Jak3-mediated IL2-induced Stat5 phosphorylation in mouse CTLL cells by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653969BDBM50653969(CHEMBL6144336)
Affinity DataIC50: 500nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653965BDBM50653965(CHEMBL6133260)
Affinity DataIC50: 540nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653966BDBM50653966(CHEMBL6120374)
Affinity DataIC50: 967nMAssay Description:Inhibition of Jak3-mediated IL2-induced Stat5 phosphorylation in mouse CTLL cells by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProteasome subunit beta type-5(Human)
Indian Institute of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653971BDBM50653971(CHEMBL6147556)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of HCV NS5A Q30R mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed