Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50022855
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655178BDBM50655178(CHEMBL6151388)
Affinity DataIC50: 380nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614096BDBM50614096(CHEMBL2324726)
Affinity DataIC50: 690nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 511638BDBM511638(US11059801, Compound D-1 | US11059801, Compound D-...)
Affinity DataIC50: 950nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655179BDBM50655179(CHEMBL6141861)
Affinity DataIC50: 1.42E+3nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65454BDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 1.71E+3nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65456BDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataIC50: 2.06E+3nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618118BDBM50618118(CHEMBL5413040)
Affinity DataIC50: 2.60E+3nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070114BDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataIC50: 3.26E+3nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed