Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50022853
TargetHistone-lysine N-methyltransferase NSD2(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598859BDBM50598859(CHEMBL5200945)
Affinity DataKd:  91nMAssay Description:Agonist activity at human native full length ERalpha by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD3(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555101BDBM50555101(CHEMBL4778517)
Affinity DataKd:  166nMAssay Description:Antagonist activity at human native full length ERalpha by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHepatoma-derived growth factor-related protein 2(Homo sapiens)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655132BDBM50655132(CHEMBL6148757)
Affinity DataKd:  3.80E+4nMAssay Description:Agonist activity at human native full length ERalpha by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655132BDBM50655132(CHEMBL6148757)
Affinity DataKd:  3.80E+4nMAssay Description:Agonist activity at human native full length ERalpha by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655132BDBM50655132(CHEMBL6148757)
Affinity DataKd:  3.80E+4nMAssay Description:Antagonist activity at human native full length ERalpha by cell-based transcriptional activation assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655133BDBM50655133(CHEMBL6151428)
Affinity DataKd:  4.20E+4nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655134BDBM50655134(CHEMBL6163049)
Affinity DataKd:  4.70E+4nMAssay Description:Inhibition of KIT (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655135BDBM50655135(CHEMBL6092080)
Affinity DataKd:  1.42E+5nMAssay Description:Inhibition of BRK (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655136BDBM50655136(CHEMBL6170432)
Affinity DataKd:  1.47E+5nMAssay Description:Inhibition of LCK (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655137BDBM50655137(CHEMBL6120745)
Affinity DataKd:  2.16E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKd:  2.59E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655139BDBM50655139(CHEMBL6103493)
Affinity DataKd:  2.85E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655138BDBM50655138(CHEMBL4537359)
Affinity DataKd:  2.85E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655140BDBM50655140(CHEMBL6149026)
Affinity DataKd:  3.22E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655141BDBM50655141(CHEMBL6144141)
Affinity DataKd:  3.63E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655142BDBM50655142(CHEMBL6103501)
Affinity DataKd:  3.66E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655143BDBM50655143(CHEMBL162438)
Affinity DataKd:  3.70E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655144BDBM50655144(CHEMBL4539250)
Affinity DataKd:  5.09E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655145BDBM50655145(CHEMBL6133415)
Affinity DataKd:  5.26E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655146BDBM50655146(CHEMBL6150335)
Affinity DataKd:  5.40E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655147BDBM50655147(CHEMBL6141992)
Affinity DataKd:  5.90E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 152261BDBM152261(US8993552, 4H8 Compound 42)
Affinity DataKd:  6.00E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPC4 and SFRS1-interacting protein(Human)
KU Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655148BDBM50655148(CHEMBL6150276)
Affinity DataKd:  7.00E+5nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed