Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50022757
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447758BDBM50447758(CHEBI:9287 | NSC-45383 | Nigrin | Rufocromomycin |...)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653948BDBM50653948(CHEMBL6146106)
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653938BDBM50653938(CHEMBL6102620)
Affinity DataIC50: 90nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653948BDBM50653948(CHEMBL6146106)
Affinity DataIC50: 450nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653948BDBM50653948(CHEMBL6146106)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653951BDBM50653951(CHEMBL6143647)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653938BDBM50653938(CHEMBL6102620)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447761BDBM50447761(CHEMBL60908)
Affinity DataIC50: 2.01E+3nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653947BDBM50653947(CHEMBL6144840)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447758BDBM50447758(CHEBI:9287 | NSC-45383 | Nigrin | Rufocromomycin |...)
Affinity DataIC50: 2.95E+3nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653945BDBM50653945(CHEMBL6147030)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653954BDBM50653954(CHEMBL6142015)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653953BDBM50653953(CHEMBL6134713)
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653938BDBM50653938(CHEMBL6102620)
Affinity DataIC50: 5.88E+3nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653946BDBM50653946(CHEMBL6102581)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653952BDBM50653952(CHEMBL6160380)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653955BDBM50653955(CHEMBL6152758)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653949BDBM50653949(CHEMBL6091952)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653940BDBM50653940(CHEMBL6102966)
Affinity DataIC50: 3.54E+4nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653941BDBM50653941(CHEMBL6146876)
Affinity DataIC50: 3.54E+4nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653942BDBM50653942(CHEMBL6151892)
Affinity DataIC50: 4.99E+4nMAssay Description:Inhibition of tryptophan 2,3-dioxygenase by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653943BDBM50653943(CHEMBL6152514)
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in mouse B16 cells assessed as kynurenine formation by adjusted cell-based spectrophotometryMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653950BDBM50653950(CHEMBL6152941)
Affinity DataIC50: 9.09E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653944BDBM50653944(CHEMBL6151231)
Affinity DataIC50: 9.41E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Daegu Gyeongbuk Medical Innovation Foundation (K-MEDI hub)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653939BDBM50653939(CHEMBL6161377)
Affinity DataIC50: 1.10E+5nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed