Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022846
TargetD(1A) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180913BDBM50180913(7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-...)
Affinity DataKi:  0.390nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(2) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654971BDBM50654971(CHEMBL3753266)
Affinity DataKi:  1.5nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1B) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180913BDBM50180913(7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-...)
Affinity DataKi:  1.5nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1A) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088341BDBM50088341(7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azec...)
Affinity DataKi:  1.90nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1B) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654971BDBM50654971(CHEMBL3753266)
Affinity DataKi:  1.90nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1B) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654970BDBM50654970(CHEMBL3752512)
Affinity DataKi:  3nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1A) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180921BDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  4nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetATP-dependent translocase ABCB1(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654972BDBM50654972(CHEMBL6152259)
Affinity DataIC50: 4.20nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1B) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088341BDBM50088341(7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azec...)
Affinity DataKi:  7.5nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(4) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180913BDBM50180913(7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-...)
Affinity DataKi:  11nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1B) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180921BDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  15nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(2) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180913BDBM50180913(7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-...)
Affinity DataKi:  18nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(3) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654971BDBM50654971(CHEMBL3753266)
Affinity DataKi:  18nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(3) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654970BDBM50654970(CHEMBL3752512)
Affinity DataKi:  24nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1A) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654971BDBM50654971(CHEMBL3753266)
Affinity DataKi:  40nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(2) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088341BDBM50088341(7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azec...)
Affinity DataKi:  45nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(2) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654970BDBM50654970(CHEMBL3752512)
Affinity DataKi:  45nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(1A) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654970BDBM50654970(CHEMBL3752512)
Affinity DataKi:  60nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(4) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654971BDBM50654971(CHEMBL3753266)
Affinity DataKi:  72nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(3) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180921BDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  87nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(4) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180921BDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  99nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(4) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088341BDBM50088341(7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azec...)
Affinity DataKi:  109nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(4) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654970BDBM50654970(CHEMBL3752512)
Affinity DataKi:  188nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetD(2) dopamine receptor(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180921BDBM50180921(6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]ben...)
Affinity DataKi:  190nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAcetylcholinesterase(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654974BDBM50654974(CHEMBL6142682)
Affinity DataKi:  4.90E+3nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654973BDBM50654973(CHEMBL6149288)
Affinity DataIC50: 7.10E+3nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAcetylcholinesterase(Human)
Peoples' Friendship University of Russia (RUDN University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654973BDBM50654973(CHEMBL6149288)
Affinity DataIC50: 1.40E+4nMAssay Description:Inverse agonist activity at human RORgammat LBD by M1H cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed