Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50023535
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097869BDBM50097869(CHEMBL3589662)
Affinity DataIC50: 6nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK4(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664923BDBM50664923(CHEMBL6173699)
Affinity DataIC50: 14nMAssay Description:Inhibition of CLK4 (unknown origin) by LanthaScreen kinase binding assay relative to controlMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664923BDBM50664923(CHEMBL6173699)
Affinity DataIC50: 26nMAssay Description:Inhibition of CLK4 (unknown origin) by radiometric assay relative to controlMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664923BDBM50664923(CHEMBL6173699)
Affinity DataIC50: 28nMAssay Description:Inhibition of GSG2 (haspin) (unknown origin) by Adapta kinase activity assay relative to controlMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664923BDBM50664923(CHEMBL6173699)
Affinity DataIC50: 35nMAssay Description:Inhibition of human His-tagged DYRK1A extracted from Escherichia coli assessed as residual activity using gamma-32 ATP and KKISGRLSPIMTEQ as substrat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664920BDBM50664920(CHEMBL6171601)
Affinity DataIC50: 52nMAssay Description:Inhibition of human His-tagged DYRK1A extracted from Escherichia coli assessed as residual activity using gamma-32 ATP and KKISGRLSPIMTEQ as substrat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664924BDBM50664924(CHEMBL6175513)
Affinity DataIC50: 54nMAssay Description:Inhibition of human His-tagged DYRK1A extracted from Escherichia coli assessed as residual activity using gamma-32 ATP and KKISGRLSPIMTEQ as substrat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363797BDBM50363797(CHEMBL1947110)
Affinity DataIC50: 67nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363802BDBM50363802(CHEMBL1947105)
Affinity DataIC50: 74nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664923BDBM50664923(CHEMBL6173699)
Affinity DataIC50: 76nMAssay Description:Inhibition of GSG2 (haspin) (unknown origin) by radiometric assay relative to controlMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100152BDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 80nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664921BDBM50664921(CHEMBL6173104)
Affinity DataIC50: 105nMAssay Description:Inhibition of human His-tagged DYRK1A extracted from Escherichia coli assessed as residual activity using gamma-32 ATP and KKISGRLSPIMTEQ as substrat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664922BDBM50664922(CHEMBL6176357)
Affinity DataIC50: 116nMAssay Description:Inhibition of human His-tagged DYRK1A extracted from Escherichia coli assessed as residual activity using gamma-32 ATP and KKISGRLSPIMTEQ as substrat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026598BDBM50026598(CHEMBL3335356)
Affinity DataIC50: 200nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445253BDBM50445253(CHEMBL1232500)
Affinity DataIC50: 240nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026599BDBM50026599(CHEMBL3335350)
Affinity DataIC50: 400nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026622BDBM50026622(CHEMBL408982)
Affinity DataIC50: 930nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Universite Claude Bernard Lyon 1

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026611BDBM50026611(CHEMBL3335361)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of DYRK1A (126-490) (unknown origin) extracted from bacteria suing 33P-ATP by radioactive filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed